POLY 371 |
| Model tissue engineering scaffolds based on a photopolymerized dimethacrylate resin were prepared for various structure-function characterizations, including scaffold structure, mechanical properties, and optical imaging of cell attachment. Scanning electron microscopy and X-ray microcomputed tomography confirmed that the scaffold structure could be controlled by the size distribution of NaCl porogen. The mechanical properties such as modulus increased as the porogen size increased. The scaffolds were also seeded with osteoblasts, cultured between 3 d to 18 d, and examined using confocal microscopy. Optical images of cells could be obtained at over 400 micron beneath the surface of the scaffold due to the amorphous glassy nature of the polymer.
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7th International Biorelated Polymers Symposium
1:30 PM-5:30 PM, Tuesday, 12 September 2006 San Francisco Marriott -- Salon 14/15, Oral
Division of Polymer Chemistry |