ANYL 82 |
| Organic matrices such as dithranol and retinoic acid are commonly used in MALDI-TOF MS analysis of polymers. This often leads to matrix signals at m/z below ~1000 Da which severely compromise the usefulness of this region of the mass spectrum. Other research groups have reported the use of inorganic particles as a substitute for organic matrices. However, these prior studies have mainly focused on biological samples with one study involving 200 Da polyethylene glycol. In this study, we have investigated the use of inorganic particles, e.g., SiO2 and ZnO nanorods, as alternate matrices. Polystyrene and polyethylene glycol with molecular weights up to 2000 Da have been successfully analyzed. In this presentation, we will also discuss results of our MALDI analyses of polymers using gold coatings.
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General Papers
7:00 PM-9:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster
Division of Analytical Chemistry |