ANYL 77 |
| One drawback of electrospray as an ionization source for mass spectrometry is the low efficiency of ion transmission into the MS. An atmospheric pressure ion lens has been used to improve analyte signal intensity and stability. This work is a systematic study of the effect of lens parameters, including voltage, on electrospray performance. Preliminary results show that the ion lens allows the generation of an electrospray over a wide range of sprayer voltages. With increasing ion lens voltage, the maximum signal intensity increases in magnitude and shifts to higher sprayer voltages. 3D finite element method modeling of the ion source showed that a very similar electric field was generated when maximum signal was obtained using each ion lens voltage setting. The increase in signal magnitude with increasing ion lens voltage is attributed to flattening of equipotential lines in front of the sprayer tip, leading to less divergent ion trajectories. |
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General Papers
7:00 PM-9:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster
Division of Analytical Chemistry |