CINFMonday, 27 March 2006

9:00 AM-11:30 AM Georgia World Congress Center -- B302, Oral
DeNovo Design and Synthetic Accessibility
Organizer:Johann Gasteiger
9:00 AMStructure and reaction based evaluation of synthetic accessibility
Johann Gasteiger, Thomas Seidel, Krisztina Boda, Achim Herwig, Oliver Sacher
9:30 AMAlgorithms and cancer drugs: In silico design of S100B ligands to block p53 binding
John L. Whitlow, Yumin Li
10:00 AMClosing the loop: From high-throughput screening to synthesis of novel protein displacers
N. Sukumar, Curt M. Breneman, Steven M. Cramer, James A. Moore, Kristin P. Bennett, Mark J. Embrechts, Min Li, Jia Liu, Long Han
10:30 AMDeNovo design tools for the generation of synthetically accessible ligands
A. Peter Johnson, Krisztina Boda, Shane Weaver, Aniko Valko, Vilmos Valko
11:00 AMFlexNovo: Structure-based searching in large fragment spaces
Jörg Degen, Matthias Rarey

DeNovo Design and Synthetic Accessibility -- Next Session

Symposium Grid -- Division of Chemical Information -- Session Listing

Symposium Grid -- Drug Discovery -- Session Listing

The 231st ACS National Meeting, Atlanta, GA, March 26-30, 2006