ANYL 161 |
| Facilitated transport of molecules through binding site doped Nanochannel is based on one basic concept that the molecules having stronger binding affinity with the binding site in nanochannel tend to be transported faster than the molecules with less affinity with binding site. DNA functionalized nanotube membranes have been used before for selectively transporting complementary DNA with single-mismatch discrimination. To further investigate the facilitated transport phenomena occurring in this modified nanotubes, we designed a new system based on alumina nanotube membrane template. Silica nanotubes formed in the alumina nanotubes was further modified with aldehyde silane to immobilize amine-modified DNAs onto the inner wall of the nanotube membranes. Optimization of the system was achieved by controlling different parameters affecting the selectivity, which includes DNA carrier density on the nanotubes, feed concentrations, binding affinity and the diameter of nanotubes. |
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General Session
7:00 PM-9:00 PM, Sunday, 26 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster
Division of Analytical Chemistry |