TOXITuesday, 30 August 2005

6:00 PM-10:00 PM Washington DC Convention Center -- Hall A, Poster
Poster Presentations and Rewards
Organizer:Trevor M Penning
Solution conformations of the major (+)-trans-anti-BPDE-N2-guanine adducts in GG dinucleotide mutation hot spots
Fabian A. Rodriguez, Qian Ruan, Chin Lin, Shantu Amin, Nicholas E. Geacintov
Base sequence and conformational effects on time-resolved fluorescence decay profiles of covalent BPDE-N2-dG adducts in DNA
Yijin Tang, Alexander Durandin, Nathaniel Stanley, Sofia Fayngold, Alexander Kolbanovskiy, Nicholas E. Geacintov
Molecular dynamics studies of the major DNA adduct from a tumorigenic metabolite of benzo[a]pyrene in replicative and bypass polymerases
Pingna Xu, Olga Rechkoblit, Dinshaw J Patel, Nicholas E. Geacintov, Suse Broyde
4-OHEN-C adduct structures in DNA duplexes: Molecular dynamics studies
Shuang Ding, Robert Shapiro, Nicholas E. Geacintov, Suse Broyde
Replication of DNA sequences with equine estrogen metabolite 4-OHEN-dC adducts catalyzed by A- and Y- family Polymerases in vitro
Dandan Chen, Alexander Kolbanovskiy, Anant Shastry, Minsun Chang, Judy L. Bolton, N. E. Geacintov
Mass spectral analysis of DNA polymerase Dpo4 bypass reaction products formed with 1,N2-ethenoguanine
Hong Zang, Angela K. Goodenough, Joeng-Yun Choi, Martin Egli, F. P. Guengerich
Elucidating the incorporation of dCTP opposite an N-(deoxyguanosin-8-yl)-2-acetyl-aminofluorene adduct (AAF-dG) within the Y-family DNA polymerase Dpo4 by molecular dynamics
Lihua Wang, Suse Broyde
19F NMR and CD studies on the sequence effect of aminofluorene and fluoroaminofluorene-modified NarI sequences
Yuyuan Li, Li Zhang, Lan Gao, M. Paul Chiarelli, Bongsup Cho
Sequence effect on the conformational heterogeneity of aminofluorene and fluoroaminofluorene-modified DNA: UV thermomelting and CD studies
Rhijuta D'Mello, Srinivasa Rao Meneni, Lan Gao, Paul Chiarelli, Bongsup Cho
Probing the sequence effect on the conformational heterogeneity of fluoroaminofluorene-modified DNA duplexes by 19F NMR
Srinivasa Rao Meneni, Bongsup Cho
Electrophoretic mobility shift assay on the formation of Klenow fragment exo-/fluoroaminofluorene-modified template-primer complexes using IRDye-700-labeled oligonucleotides
Fengting Liang, Aftab Ahmed, Bongsup Cho
Kinetic analysis of the sequence context effects on polymerization catalyzed by HIV-1 Reverse Transcriptase
Rio Yamanaka, John Termini
Structures of a food carcinogen-DNA adduct in replicative and bypass polymerases using molecular dynamics simulations
Ling Zhang, Robert Shapiro, Suse Broyde
2-Amino-1,7-dimethylimidazo[4,5-g]quinoxaline (7-MeIgQx): A novel and abundant mutagenic heterocyclic aromatic amine formed in grilled beef
Robert J. Turesky, David LeMaster, Lynn Mcnaughton, Ricky D. Holland, Rebecca W. Wu, James S. Felton
Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in the recognition sequence of the narI restriction enzyme, a hotspot for -2 bp deletions
Feng Wang, C. Eric Elmquist, Carmelo J. Rizzo, Michael P. Stone
In vitro replication and repair studies of a novel intrastrand crosslink lesion G[8-5]C
Chunang Gu, Yinsheng Wang
Disulfide trapping and structural characterization of complexes of DNA glycosylases with undamaged DNA
Anirban Banerjee, Gregory L. Verdine
Repair of oxidized guanines by OG glycosylases
Nirmala Krishnamurthy, Kazuhiro Haraguchi, Carissa J. Wiederholt, James G. Muller, Cynthia J. Burrows, Marc M. Greenberg, Sheila S. David
Structural and thermodynamic features of spiroiminodihydantoin oxidative lesions in duplex DNA by molecular dynamics simulations
Lei Jia, Vladimir Shafirovich, Robert Shapiro, Nicholas E. Geacintov, Suse Broyde
Biochemical characterization of Formamidopyrimidine lesions
Jennifer N. Patro, Carissa J. Wiederholt, Yu Lin Jiang, Kazuhiro Haraguchi, Marc M. Greenberg
AEI: Analysis of 2-deoxyribonolactone in DNA using cysteine conjugates
Liang Xue, Kousuke Sato, Marc M. Greenberg
In vitro DNA ligation of oligodeoxynucleotides containing oxidized purine lesions using bacteriophage T4 DNA ligase
Xiaobei Zhao, James G. Muller, Mohan Halasyam, Sheila S. David, Cynthia J. Burrows
Defining the basis for the unusual sequence selectivity of nitrosoperoxycarbonate-induced guanine oxidation
Yelena Margolin, Vladimir Shafirovich, Nicholas E. Geacintov, Peter C. Dedon
Oxidative DNA damage induced by carbonate radical anions: Laser flash photolysis and gel electrophoresis studies
Young Ae Lee, Byeong Hwa Yun, Conor Crean, Yelena Margolin, Peter C. Dedon, Nicholas E. Geacintov, Vladimir Shafirovich
Sensitive methods to quantify C4 deoxyribose lesions produced by bleomycin and gamma-radiation
Xinfeng Zhou, Bingzi Chen, Peter C. Dedon
DNA oxidative damage by analogs of diterpenone catechol
Miguel A. Zuniga, Mark Wehunt, Qibing Zhou
Identification and quantitation of hepatic DNA adducts in N-nitrosopyrrolidine (NPYR)-treated rats
Mingyao Wang, Yongli Shi, Yanbin Lao, Peter W. Villalta, Stephen S. Hecht
Complex products from the nitrosation of N-arylpyrrolidines
Richard N. Loeppky, Sukhjeet S Singh, Yinan Li
Toxicity screening using biocatalyst/DNA films and CapLC-MS/MS
Maricar C Tarun
Fluorescence based assay for DNA damage induced by toxic chemicals
Srividya Kailasam, Kim R Rogers
Investigation into mechanisms of hypoxia selective anticancer agents, 3-methyl-1,2,4-benzotriazine-1,4-dioxide and 3-amino-1,2,4-benzotriazine-1,4-dioxide
Venkatraman Junnotula, Ujjal Sarkar, Sarmistha Sinha, Chad Inman, Charles L Barnes, Kent S Gates
Structure activity relationship of G-N7 and G-N2 DNA monoadducts of non-cytotoxic metabolite of mitomycin C, 2, 7-diaminomitosine (2, 7-DAM)
Cristina C. Clement, Maria Tomasz
Synthesis of and DNA damage by a small Leinamycin analog
Kripa Keerthi, Kent Gates
Leinamycin: A structurally novel DNA intercalator
Joseph Szekely, Sanjay Dutta, Kent Gates
Mechanistic studies on the photosensitizing activities of 2,3 -diaminophenazine, a common contaminant in hair dyes
Patty K-L. Fu, Yao Liu, Jun-Jie Yin, Claudia Turro
Photocytotoxicity of retinol and the role of photooxidative damage
Wayne G. Wamer, Peter P. Fu, Daniel E. Falvey
Cyclooxygenase-mediated metabolism of arachidonic acid in rat intestinal epithelial cells
Seon Hwa Lee, Michelle V. Williams, Raymond N. DuBois, Ian A. Blair
Characterization of lipid hydroperoxide-derived protein modifications
Tomoyuki Oe, Seon Hwa Lee, Jasbir S. Arora, Ian A. Blair
Mass spectroscopic characterization of protein-based carbonyls generated by oxidative modification
Xiaochun Zhu, Quan Yuan, Lawrence M Sayre
Chemical model for the redox regulation of protein tyrosine phosphatase 1B (PTP1B)
Santhosh Sivaramakrishnan, Kripa Keerthi, Kent S. Gates
Alkylation stress triggers ubiquitination of modified proteins
Elizabeth B. Burnette, Daniel C. Liebler
Identification of a peptide adduct formed with a phase II conjugate
William H. Connors, Jimmy Flarakos, Paul L. Skipper, John S. Wishnok, S. Tannenbaum
Metal-catalyzed oxidation and liquid chromatography mass spectrometry for detection of amyloid-b modifications
Koichi Inoue, Tomoyuki Oe, Ian A. Blair
LC/MS identification of gallic acid and procyanidins from grape seed extract with anti-cancer activity in DU145 human prostate carcinoma cells
Ravikanth Veluri, John A. Thompson, Rajesh Agarwal, Chapla Agarwal
Metabolic activation of PAH trans-dihydrodiols by human Aldo-Keto Reductase 1B10
Amy M. Quinn, Trevor M Penning
PAH o-quinones produced by the AKR pathway predominantly generate abasic sites and 8-oxo-dGuo via reactive oxygen
Jong Heum Park, Trevor M. Penning
Measuring PAH-induced oxidative stress in human lung cells
Kirk A. Tacka, Trevor M. Penning
Evaluating the scientific evidence for potential reduced-risk tobacco products
Amy M. Brownawell, Michael C. Falk, Keith Lenghaus, Kara D. Lewis, Paula M. Nixon, Catherine St. Hilaire
Mechanism-based inactivation of human cytochrome P450 2B6 by substituted phenyl diaziridines
Satish Goud Puppali, John M. Rimoldi, Chitra Sridar, Yoshimasa Kobayashi, Paul F. Hollenberg
Synthesis of fenthion sulfoxide and fenoxon sulfoxide enantiomers: Effect of sulfur chirality on acetylcholinesterase activity
Rama Sarma Gadepalli, Mae Nillos, Jay Gan, Daniel Schlenk, Frank R. Fronczek, John M. Rimoldi
Interleukins 2 and 12 do not remediate altered MAP kinases p38 and p44/42 phosphorylation in tributyltin-exposed human natural killer cells
Aloice O. Aluoch, Margaret M. Whalen
Anorexic region in tissue by theory of Krogh in cartesian coordinates
Kal Renganathan Sharma
Paper Withdrawn
Detoxification of Hg2+, As3+ and Pb2+ metal ions from wastewater by biosorption using modified and unmodified coconut fiber: pH, temperature and particle size effects
Jude C. Igwe, Augustus A Abia, Stephinie I Okenwa, Benedict C. Gbaruko, Emmanuel C Nwokennaya
Levels of toxic elements in soils of abandoned waste dump site
Nnenna E. Okoronkwo, A. O. Ano, Jude C. Igwe, E. C. Onwuchekwa, I. Nnorom
Integrated 2-bed adsorption system and biofiltration for treatment of waste gas streams
Daekeun Kim, Zhangli Cai, George A Sorial
Restricted adsorbent PSD hindered oligomerization of phenolic compounds
Qiuli Lu, George A. Sorial

Symposium Grid -- Division of Chemical Toxicology -- Session Listing

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005