ANYL 26 |
| New dinitrophenyl substituted chiral sugar derivatives are synthesized. The chiral selectors are covalently bonded to functionalized 5µm spherical porous silica gel and evaluated as Chiral Stationary Phases (CSPs) for High Performance Liquid Chromatography (HPLC). A variety of different aryl groups are investigated and compared in terms of their ability in chiral separation. The position of dinitro groups on the phenyl ring, the degree of substitution, and the bonding strategy affect the performance of chiral separation greatly. The new chiral stationary phases successfully resolved hundreds of racemic compounds. The dual nature retention behavior of Room Temperature Ionic Liquids (RTILs) makes them attractive as stationary phases for Gas Chromatography (GC). A variety of chiral ionic liquids based on various chiral sugars are synthesized and characterized. The chiral resolution abilities of these RTILs in GC are evaluated. |
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General Papers
8:30 AM-11:10 AM, Sunday, 28 August 2005 Washington DC Convention Center -- 153, Oral
Sci-Mix
Division of Analytical Chemistry |