Pd-catalyzed [3+2] cycloaddition reaction of carbon dioxide

ORGN 385

George E. Greco, ggreco@goucher.edu, Brittany L. Gleason, Tiffany A. Lowery, and Matthew J. Kier. Department of Chemistry, Goucher College, 1021 Dulaney Valley Road, Baltimore, MD 21204
Carbon dioxide and 2-(acetoxymethyl)-3-(trimethylsilyl)propene participate in a palladium-catalyzed [3+2] cycloaddition reaction to form a g-butyrolactone in good yield under mild conditions (1 atmosphere of pressure and 50 degrees). This paper will discuss the factors leading to successful product formation, and our efforts at uncovering the scope, selectivity, and mechanism of this reaction.


Bioorganic, Metal-Mediated Reactions, and Molecular Recognition
8:00 PM-10:00 PM, Tuesday, 30 August 2005 Washington DC Convention Center -- Hall A, Poster

8:00 PM-10:00 PM, Monday, 29 August 2005 Washington DC Convention Center -- Hall A, Sci-Mix

Division of Organic Chemistry

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005