Anion encapsulation within metalated cryptophanes

ORGN 471

Robert M. Fairchild, rmf25@georgetown.edu and K. Travis Holman, kth7@georgetown.edu. Department of Chemistry, Georgetown University, 37th and O St. NW, Washington, DC 20057

 

Anion binding and recognition is an important field in supramolecular chemistry due to its relevance in biochemical systems, waste treatment, catalysis and medicine.  Anion receptors based on hydrogen bonding and Lewis acid centers have been widely utilized and studied.  The recent development of exteriorly modified cryptophanes, by electron withdrawing transition-metal fragments, will be presented.  The resulting cationic capsules entrap anions, highlighting rather uncommon anion-arene interactions.  The modification has been shown to have considerable ramifications on the host's:  i) electronic binding preferences, ii) effective interior volume, and iii) kinetics of guest exchange.  Though these hosts encapsulate a wide range of anions, from Cl- to SbF6-, some remarkable selectivities have been observed.

 

 

 

 

 

 

Bioorganic, Metal-Mediated Reactions, and Molecular Recognition
8:00 PM-10:00 PM, Tuesday, 30 August 2005 Washington DC Convention Center -- Hall A, Poster

Sci-Mix
8:00 PM-10:00 PM, Monday, 29 August 2005 Washington DC Convention Center -- Hall A, Sci-Mix

Division of Organic Chemistry

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005