The investigation of Ring Expansion in beta-lactam derivatives


Chuljin Ahn,, Sun-Joo Oh1, Jin-Ryul Ha1, and Juhee Park2. (1) Department of Chemistry, Changwon National University, 9 Sarim-Dong, Changwon, KyungNam, 641-773, South Korea, (2) Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742
The base induced ring opening of -lactam derivatives with LDA gave -lactam derivatives stereoselectively. The -lactam derivatives were formed stereoselectively depending on C-3 substituent of the -lactam derivatives