Countless biologically active indole and carbazole alkaloids have been isolated from natural sources. Indole-2,3-quinodimethane (1) is a reactive intermediate that has been generated by several groups for the synthesis of indole-containing natural products. However, no stable example of indole-2,3-quinodimethane has been synthesized. The paper will present our approaches to the generation of potentially stable analogs of indole-2,3-quinodimethane.
Asymmetric Reactions, Heterocycles, Aromatics, Combinatorial, and Physical Organic Chemistry
8:00 PM-10:00 PM, Wednesday, 31 August 2005 Washington DC Convention Center -- Hall A, Poster