Magnetic-field-assisted bioseparation and drug delivery by magnetic silica/magnetite composite nanotubes

ANYL 152

Sang Jun Son, triaza@gmail.com1, Jonathan Reichel, jreichel@umd.edu1, Bo He, ripplehe@yahoo.com1, Mattan Schuchman, mattanster@gmail.com1, Xia Bai, xbai@umd.edu1, and Sang Bok Lee, slee@umd.edu2. (1) Department of Chemistry & Biochemistry, University of Maryland, 0107 Chemistry Building, University of Maryland, College Park, MD 20742, (2) Department of Chemistry and Biochemistry, University of Maryland, 0107 Chemistry Building, University of Maryland, College Park, MD 20742
Magnetic nanoparticles have been intensively investigated for their applications in drug delivery, biosensors, chemical and biochemical separation and concentration, enzyme encapsulation, and contrast enhancement in magnetic resonance imaging (MRI). In most applications, spherical nanoparticles have been used. However, spherical magnetic nanoparticles still need to be improved for controlling particle sizes, surface functionalizations, and their environmental compatibility due to the structural limitation of spherical particles when multifuntionality is required on their surfaces. Template-synthesized magnetic nanotubes can be an attractive solution due to their distinctive structural attributes over conventional spherical nanoparticles. Therefore, by combining the attractive tubular structure with magnetic property, the magnetic nanotube can be an ideal candidate for the multifunctional nanomaterial toward biomedical applications, such as targeting drug delivery with MRI capability. Here, we successfully synthesized magnetic silica/magnetite composite nanotubes and their useful applications for biochemical separations and drug delivery were investigated.

 

General Papers
7:00 PM-9:00 PM, Sunday, 28 August 2005 Washington DC Convention Center -- Hall A, Poster

Sci-Mix
8:00 PM-10:00 PM, Monday, 29 August 2005 Washington DC Convention Center -- Hall A, Sci-Mix

Division of Analytical Chemistry

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005