Comparison of topical antioxidants for prevention of UV radiation damage

AGFD 66

Katie A. Terrana, Terranak2@scranton.edu and Joe A. Vinson, vinson@scranton.edu. Department of Chemistry, University of Scranton, Monroe Avenue, Scranton, PA 18510
Skin cancer is caused by over exposure to UV radiation from the sun. It is well known from epidemiological studies that intake of antioxidants protects against many kinds of cancer. This experiment was designed to compare antioxidants from green tea, black tea, grape seed, and cranberry extracts in topical ointment treatments as effective inhibitors of skin cancer in a UV-irradiated mouse model. A control group with no added antioxidant in the topical treatment was used to compare skin damage and biochemical indices with antioxidant groups. All of the antioxidants were significantly effective at inhibiting skin damage and protein and lipid oxidation as a result of an increase in skin antioxidants. A future study will be conducted to test the topical absorption of the antioxidants in humans.
 

Sci-Mix
8:00 PM-10:00 PM, Monday, 14 March 2005 Convention Center -- Sails Pavilion, Sci-Mix

Division of Agricultural & Food Chemistry

The 229th ACS National Meeting, in San Diego, CA, March 13-17, 2005