COLL 181 |
| Maozi Liu, Department of Chemistry, University of California, One Shields Ave., Davis, CA 95616 and Gang-Yu Liu, Department of Chemistry, University of California, Davis, One Shields Ave, Davis, CA 95616. |
| Nanostructures of thiolated single-stranded DNA (ssDNA) are produced using an atomic force microscopy (AFM)-based lithography technique - nanografting. Under high shear force, AFM tips displace resist molecules within a self-assembled monolayer, while thiolated ssDNA molecules adsorb chemically from solution onto the exposed gold. Nanostructures of ssDNA are characterized directly and in situ using the same tip. This approach allows for the highest precision, smallest size and for multiple components production. The hybridization of the DNA within the nanostructures has been successfully monitored without using labels or tags by in situ AFM imaging. The impact of molecular level parameters on hybridization will also be discussed. |
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Posters: Fundamental Research in Surface and Colloid Chemistry
6:00 PM-8:00 PM, Monday, March 29, 2004 Disneyland -- North Exhibit Hall, Poster
Division of Colloid and Surface Chemistry |