COLL 391 |
| Françoise M. Winnik, Roger C. W. Liu, and Florence Ségui. Department of Chemistry and Faculty of Pharmacy, University of Montreal, C. P. 6128 succursale Centre-ville, Montreal, QC H3C 3J7, Canada |
| Fluorocarbon derivatives, which are hydrophobic and lipophobic, show limited miscibility with their hydrocarbon counterparts. In water, low molecular weight fluorocarbon and hydrocarbon amphiphiles tend to form segregated fluorocarbon-rich and hydrocarbon-rich micelles. Hybrid amphiphiles bearing fluorocarbon and hydrocarbon groups in the same molecule tend to associate into micelles with discrete fluorocarbon and hydrocarbon compartments. Such multicompartment micelles present unique colloidal features and may act as model for multidomain proteins. We have investigated several approaches towards multidomains polymeric micelles formed by the assembly in water of hydrophobically-modified polymers bearing fluorocarbon and hydrocarbon chains. Neutral polymers, polyanions, and polybetaines either grafted randomly with low levels of fluorocarbon (0.5 mol%) and hydrocarbon (0.5 mol%) chains or telechelic polymers with hydrocarbon/fluorocarbon tails have been prepared and their assembly in water and at the air/water interface was assessed by tensiometry, fluorescence spectroscopy, dynamic light scattering, isothermal titration calorimetry and AFM. |
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Symposium in Memory of Arthur W. Adamson
8:30 AM-12:10 PM, Wednesday, March 31, 2004 Marriott -- Orange County 4, Oral
Division of Colloid and Surface Chemistry |