I&EC 24 |
| Leonidas G. Bachas, Department of Chemistry, Department of Chemistry, University of Kentucky, 125 Chemistry/Physics Bldg, Rose St., Lexington, KY 40506-0055 |
| The selectivity of chemical sensors is primarily determined by the specificity of the employed recognition element. Highly selective cation membrane sensors based on macrocyclic Lewis bases have been developed. In contrast, anion sensors have yet to reach the same level of achievement, due to the slower pace in the development of molecular hosts (ionophores) for anions. Several strategies can be followed in the design of ionophores with optimal selectivity toward a particular anion. The topology of the ionophore and the presence of functional groups that are organized to complement the size and shape of the targeted anion determine the ion-ionophore interactions and consequently the selectivity of the resulting sensors. Examples of ionophores and their use in the development of potentiometric and optical sensors for anions (e.g., chloride and sulfate) will be discussed. Additionally, our most recent efforts in integrating sensors and sensing arrays within microfluidic devices will be presented. |
|
Molecular Hosts for Anion Binding (sponsored by Separation Science & Technology Subdivision)
1:30 PM-4:55 PM, Sunday, March 28, 2004 Marriott -- Orange County 1, Oral
Division of Industrial and Engineering Chemistry |