Poperties of novel amino acid derivatives at the air/water and oil/water interface

COLL 224

Mark R Watry, Department of Chemistry, Department of Chemistry, Gonzaga University, 502 E BOONE AVE, Spokane, WA 99258
N-acyl derivatives of amino acids and small peptides have been shown to be good differentiation agents for various cancer cells. The study of these amino acid derivatives can yield insight into the interactions between amino acids in peptides and proteins at liquid interfaces because the long chains anchor more of the amino acid residues at the surface. A variety of N-acylamino acids were prepared and surface pressure isotherms have been determined for these compounds adsorbed to the air/water and oil/water interfaces.