COLL 472 |
| Alice A. Deckert, Christine Delaney, Kelley Anderson, and Katherine M. Mullaugh. Department of Chemistry, Allegheny College, Meadville, PA 16335 |
| The kinetics of reactions involving an active succinimide ester attached to silver colloids by thiolated tethers have been investigated using surface enhanced raman spectroscopy (SERS) for several solution phase reactants, tether lengths, and surface concentrations of active esters. The reactions of BOC-protected cystein and BOC-protected histidine with active esters on the surface of the colloids both followed pseudo-first order kinetics. The rates of the reaction were enhanced for thioctic acid tethers over propionic acid tethers. This is consistent with a less densely packed thioctic acid layer and mixed-second order kinetics overall. Glucose-oxidase also followed mixed-second order kinetics with a rate constant of 0.28 mM-1s-1. |
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Symposium in Memory of Arthur W. Adamson
8:30 AM-11:50 AM, Thursday, April 1, 2004 Marriott -- Orange County 3, Oral
Division of Colloid and Surface Chemistry |