Surface chemistry and microcapsule/nanocapsule formation

COLL 525

Curt Thies, Thies Technology, 921 American Pacific Dr, Suite 309, Henderson, NV 89014
Microcapsules and nanocapsules are small particles loaded with a desired active agent. They have high surface areas, so their formation and properties are controlled by surface forces. The purpose of this presentation is to illustrate how surface chemistry affects capsule formation. Two capsule properties of specific interest are particle size and rate of release of active agents from the particles. The complex nature of capsule formation processes often makes it difficult to properly define what components in a specific system control these properties. Although interfacial tension measurements provide a means of monitoring changes in interfacial energy that occur during capsule formation, interpretation of such data can be difficult due to the multi-component nature of typical encapsulation systems. This will be shown by using various interfacial tension measurements obtained for encapsulation proceses based on complex coacervation and interfacial polymerization.