COLL 451 |
| Subodh Dutta1, Tushara Gunasinghe1, Subra Muralidharan1, and Thomas W. Bell2. (1) DEpartment of Chemistry, Western Michigan University, Kalamazoo, MI 49008, (2) Department of Chemistry/216, University of Nevada, Reno, NV 89557-0020 |
| Molecules capable of sensing nerve gas agents such as sarin and VX by interacting with them are important for homeland security applications. Molecules that can interact with nerve gas agents and result in an increase in luminescence are especially attractive for the design of selective and sensitive sensors for chemical warfare agents. Our recent study has demonstrated that isoquinoline and its derivatives are extremely sensitive receptors for nerve gas agents. Isoquinoline forms adducts with nerve gas agents such as DCP by the elimination of halides, which have substantially higher luminescence intensity, compared to free isoquinoline. Adduct formation between isoquinoline and DCP has been demonstrated in solvents such as chloroform, methanol, and acetonitrile by luminescence, multinuclear NMR and IR spectroscopies as a function of the concentrations of isoquinoline and DCP. The immobilization of isoquinoline on nanoparticles such as SiO2, TiO2, Au etc. are being investigated to obtain nanoparticle arrays that can be employed as sensitive and selective sensors for chemical warfare agents. The influence of these nanoparticles on the adduct formation between isoquinoline and DCP has been investigated by luminescence and NMR studies. These studies will be presented. |
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Nanoscience and Nanotechnology
2:00 PM-5:15 PM, Wednesday, March 31, 2004 Marriott -- Orange County 5, Oral
Division of Colloid and Surface Chemistry |