NUCLTuesday, March 25, 2003

8:00 AM-12:20 PM Convention Center -- Room 390,Oral
Development of High-LET Therapeutic Radiopharmaceuticals
Bismuth-213 Radiopharmaceuticals
Presiding:Saed Mirzadeh
Organizers:Martin W. Brechbiel
D. Scott Wilbur
8:00 AM Introductory Remarks
8:05 AM 58High-LET radiopharmaceuticals: Practical or pretender?
Robert Atcher
8:35 AM 59Production of actinium-225 for alpha-particle-mediated radioimmunotherapy
Rose A. Boll, Dairin W. Malkemus, Saed Mirzadeh
8:55 AM 60Alternative routes for the production of 229Th, 225Ra, and 225Ac
Marc A. Garland, Charles W. Alexander, Saed Mirzadeh
9:15 AM 61Recoil separation of 221Fr and 213Bi from 225Ac
Ann Marie Doneski Craig, Daniel J. Marsh, George K. Schweitzer, Saed Mirzadeh
9:35 AM 62The multicolumn selectivity inversion generator concept
E. Philip Horwitz, Andrew H. Bond
9:55 AM 63A multicolumn selectivity inversion generator for the production of high-purity actinium-225 for use in therapeutic nuclear medicine
Andrew H. Bond, E. Philip Horwitz, Daniel R. McAlister, Kenneth R. Givens
10:15 AM Intermission
10:30 AM 64Mesoporous sol-gels for use in clinical-scale 225Ac-213Bi generators
John W. Clavier, Saed Mirzadeh, David Depaoli, Michael Z-C. Hu
10:50 AM 65Ac-225/Bi-213 generator chemistries compatible with automation
Oleg Egorov, Matt O'Hara, Sergei I. Sinkov, Kenneth R. Givens
11:10 AM 66An automated radionuclide separation system for nuclear medical applications
Andrew H. Bond, E. Philip Horwitz, Daniel R. McAlister
11:30 AM 67Improved method for labeling DOTA analogs with 213Bi, 225Ac, and lanthanides
Tuomo K Nikula, Christos Apostolidis, Ramon Carlos-Marquez, Philippe Jehenson, Helmuth Mäcke, Simona Martin, Ali Ouadi
11:50 AM 68Development of a commercial bismuth-213 alpha-particle immunotherapy dose preparation kit
Kenneth R. Givens, A. H. Bond
12:10 PM Discussion

Development of High-LET Therapeutic Radiopharmaceuticals -- Next Session

Symposium Grid -- Division of Nuclear Chemistry & Technology -- Session Listing

The 225th ACS National Meeting, New Orleans, LA, March 23-27, 2003