IEC 198 |
| Tejal Desai, Biomedical Engineering, Biomedical Engineering, Boston University, Boston, MA 02215 |
| By utilizing fabrication techniques commonly employed in the microelectronics industry, nanoporous membranes can be fabricated present uniform and well-controlled pore sizes in the 5-50 nm range. Of particular interest is the development and characterization of well-controlled, stable, and uniform nano-dimensional membranes capable of the separation of viruses and/or proteins during the blood fractionation processes and the blocking of antibodies and complement molecules from encapsulated xenogeneic cells. The ability of the nanoporous membrane to perform size-based exclusion and controlled diffusion of relevant biomolecules was investigated. Additionally, the functionality of cells inside nanoporous environments was examined. The semipermeability of nanoporous membranes, their biocompatibility, ease in sterilization, along with their thermal and chemical stability, provide significant advantages for biomedical applications such as cell immunoisolation and controlled-release drug delivery.
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Biological Applications of Nanomaterials and Nanotechnology (sponsored by Advanced Materials & Nanotechnology Subdivision)
8:00 AM-12:05 PM, Wednesday, March 26, 2003 Convention Center -- Room 393, Oral
Division of Industrial and Engineering Chemistry |