Thermo-reversible properties of surface-immobilized hydrogels based on poly(N-alkylacrylamide)-g-poly(ethylene glycol)

PMSE 318

Dirk Schmaljohann1, Detlev Beyerlein2, Mirko Nitschke3, Stefan Zschoche2, and Carsten Werner4. (1) Department of Macromolecular Chemistry, IPF Dresden e.V, Hohe Str. 6, 01069 Dresden, Germany, (2) Institute of Polymer Research, Hohe Strasse 6, Dresden D-01069, Germany, (3) Institut fuer Polymerforschung Dresden, Hohe Strasse 6, Dresden 01069, Germany, (4) Biocompatible Materials, Institute of Polymer Research Dresden, Hohe Str. 6, Dresden, 01069, Germany
Low Pressure Plasma has been successfully applied to immobilize and crosslink thin polymer coatings based on poly(N-alkylacrylamide)-g-poly(ethyleneglycol). The thermo-reversible properties of the resulting hydrogel films were studied with ellipsometry and contact angle measurements. It was found that there are two time regimes of swelling, a dynamic swelling occurs within seconds and is complete within a few minutes, whereas the swelling equilibrium requires several days. The observed volume phase transition is more gradual for PDEAAm containing films, whereas the PNiPAAm films exhibit a sharper transition.