IEC 218 |
| Antonella Badia and Patricia Moraille. Department of Chemistry, Universite de Montreal, C.P. 6128, succursale Centre-ville, Montreal, QC H3C 3J7, Canada |
| Spatially directing the deposition of proteins and other biomolecules onto pre-defined regions of a surface is central to the development of a number of emerging technologies. In this regard, we recently demonstrated that laterally nanostructured phospholipid monolayers and bilayers can be used as selective adsorption templates. These phospholipid templates have been generated by the Langmuir-Blodgett (LB) transfer of mixed phospholipid monolayers from the air/water interface onto solid substrates and consist of nanoscale parallel stripes. These stripe patterns are composed of two saturated phopholipids in different phases (solid and fluid). We have observed that protein adsorption is limited to the more fluid phase of the phospholipid LB films. This adsorption selectivity has been used to generate well-defined protein and gold nanoparticle/protein patterns. The mechanism of stripe formation and the results of protein adsorption studies will be presented. This work expands the repertoire of template composition, pattern form, and pattern length scale usable for the nanofabrication of inorganic and biomolecular structures. |
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Biological Applications of Nanomaterials and Nanotechnology (sponsored by Advanced Materials & Nanotechnology Subdivision)
1:30 PM-4:50 PM, Wednesday, March 26, 2003 Convention Center -- Room 393, Oral
Division of Industrial and Engineering Chemistry |