IEC 215 |
| Nadrian C. Seeman, Department of Chemistry, Department of Chemistry, New York University, Waverly 1066, 100 Washington Sq. East, New York University, NY 10003 |
| Structural DNA nanotechnology uses reciprocal exchange between DNA units to produce branched DNA motifs, such as double crossover (DX), triple crossover (TX), paranemic crossover (PX) and parallelogram motifs. We combine DNA motifs to produce specific structures, using sticky-ends, edge-sharing or paranemic cohesion. We have made DNA stick-polyhedra, knots and Borromean rings. We have produced two DNA nanomechanical devices, one based on the B-Z transition and one based on sequence control. We have assembled micron-sized 2-dimensional DNA arrays from DX, TX and parallelogram motifs. We can produce specific designed patterns visible in the AFM from DX and TX molecules. We can change the patterns by changing the components, and by modification after assembly. In addition, we have generated 2D arrays from DNA parallelograms. These arrays contain cavities whose sizes can be tuned by design. In addition to specific periodic self-assembly, we have performed algorithmic constructions, corresponding to XOR operations. |
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Biological Applications of Nanomaterials and Nanotechnology (sponsored by Advanced Materials & Nanotechnology Subdivision)
1:30 PM-4:50 PM, Wednesday, March 26, 2003 Convention Center -- Room 393, Oral
Division of Industrial and Engineering Chemistry |