IEC 193 |
| A. Paul Alivisatos, Department of Chemistry, Department of Chemistry, University of California, Berkeley and Lawrence Berkeley National Laboratory, B62 Hildebrand Hall, Berkeley, CA 94720-1460 |
| Colloidal quantum dots coated with silica can be used to track the motions of cells in culture. When cells are deposited on a collagen layer that is coated with quantum dots, the cells ingest all the dots over which they pass. By imaging the resulting tracks, one can obtain a quantitative measure of cell motility, which correlates directly with metastatic potential. These experiments have been applied to a wide variety of cell lines, including invasive and non-invasive tumor cells, as well as healthy cells. The prospects of using this method for rapid and quantitative determination of metastatic potential will be discussed. |
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Biological Applications of Nanomaterials and Nanotechnology (sponsored by Advanced Materials & Nanotechnology Subdivision)
8:00 AM-12:05 PM, Wednesday, March 26, 2003 Convention Center -- Room 393, Oral
Division of Industrial and Engineering Chemistry |